Il fondo di Gio

Projects

  • DIPG Massimino
    • Maura Massimino MD, Veronica Biassoni MD, Rosalba Miceli MD, Elisabetta Schiavello MD, Monika Warmuth – Metz MD, Piergiorgio Modena PhD, Michela Casanova MD, Emilia Pecori MD, Felice Ginagaspero MD, Manila Antonelli MD, Francesca Romana Buttarelli PhD, Paolo Potepan MD, Bianca Pollo MD, Raffaele Nunziata MD, Filippo Spreafico MD, Marta Podda MD, Andrea Anichini PhD, Carlo Alfredo Clerici MD, Iacopo Sardi MD, Loris De Cecco PhD, Udo Bode MD, Ferdinand Bach PhD, and Lorenza Gandola MD.
      Results of nimotuzumab and vinolrebine, radiation and re-irradiation for diffuse pontine glioma in childhood.
      Journal of Neuro-oncology 2014, april 7.
      download pdf (in italian) (44 KB)
    • Andrea Anichini.
      Determinazione della presenza, dei livelli, e della loro evoluzione temporale, in relazione alla terapia, di un ampio spettro di molecole solubili (n=26), appartenenti alle famiglie dei fattori di crescita nei DIPG.
      download pdf (in italian) (46 KB)
  • Finocchiaro G.
    Dendritic cell immunotherapy of glioblastoma multiforme.
    download pdf (46 KB)
    • Serena Pellegatta, Pietro Luigi Poliani, Elena Stucchi, Daniela Corno, Chiara Agnese Colombo, Francesca Orzan, Maria Ravanini, and Gaetano Finocchiaro.
      Intra-tumoral dendritic cells increase efficacy of peripheral vaccination by modulation of glioma microenvironment.
      Neuro-Oncology 12(4) -377-388, 2010.
      download pdf (72 KB)
    • Gabriele Cantini, Federica Pisati, Sara Pessina, Gaetano Finocchiaro and Serena Pellegatta.
      Immunotherapy against the radial glia marker GLAST effectively triggers specific antitumor effectors without autoimmunity.
      Oncoimmunology 1:6, 884-893; September 2012.
      download pdf (163 KB)
    • Serena Pellegatta, Marica Eoli, Simona Frigerio, Carlo Antozzi, Maria Grazia Bruzzone, Gabriele Cantini, sara Nava, Elena Anghileri, Lucia Cuppini, Valeria Cuccarini, Emilio Ciusani, Marta Dossena, Bianca Pollo, Renato Mantegazza, Eugenio A. Parati and Gaetano Finocchiaro.
      The natural killer cell response and tumor debulking are associated with prolonged serviva in recurrent glioblastoma patients receiving dendritic cells loaded with autologous tumor lysates.
      Oncoimmunology 2:3, e23401; March 2013.
      download pdf (155 KB)
    • Pellegatta S, Poliani PL, Corno D, Menghi F, Ghielmetti F, Suarez-Merino B, Caldera V, Nava S, Ravanini M, Facchetti F, Bruzzone MG, Finocchiaro G.
      Neurospheres Enriched in Cancer Stem-Like Cells Are Highly Effective in Eliciting a Dendritic Cell-Mediated Immune Response against Malignant Gliomas.
      Cancer Res. 2006 Nov 1;66(21):10247-52.
      download pdf (569 KB)
    • Gabriele Cantini, Federica Pisati, Alfonso Mastropietro, Véronique Frattini, Yoichiro Iwakura, Gaetano Finocchiaro, Serena Pellegatta
      A critical role for regulatory T cells in driving cytokines profiles of Th17 cells and their modulation of glioma microenvironment.
      Cancer Immunol. Immunother. 2011 Jul DOI 10.1007/s00262-011-1069-4.
      download pdf (143 KB)
    • Gabriele Cantini, Federica Pisati, Sara Pessina, Gaetano Finocchiaro and Serena Pellegatta1
      Immunotherapy against the radial glia marker GLAST effectively triggers specific antitumor effectors without autoimmunity
      OncoImmunology 1:8, 1-10; November 2012; © 2012 Landes Bioscience.
      download pdf (198 KB)
    • Véronique Frattini, Federica Pisati, Maria Carmela Speranza, Pietro Luigi Poliani, Gianmaria Frigé, Gabriele Cantini, Dimos Kapetis, Manuela Cominelli, Alessandra Rossi, Gaetano Finocchiaro and Serena Pellegatta
      FOXP3, a novel glioblastoma oncosuppressor, affects proliferation and migration
      Oncotarget, Advance Publications, September 2012.
      download pdf (591 KB)
    • Antonella De Rosa, Serena Pellegatta, Marco Rossi, Patrizia Tunici, Letizia Magnoni, Maria Carmela Speranza, Federico Malusa, Vincenzo Miragliotta, Elisa Mori, Gaetano Finocchiaro, Annette Bakker
      A Radial Glia Gene Marker, Fatty Acid Binding Protein 7 (FABP7), Is Involved in Proliferation and Invasion of Glioblastoma Cells
      PLOS ONE, December 2012, Volume 7, Issue 12, e52113.
      download pdf (140 KB)
    • Sara Nava, Marta Dossena, Simona Pogliani, Serena Pellegatta, Carlo Antozzi, Fulvio Baggi, Cinzia Gellera, Bianca Pollo, Eugenio A. Parati, Gaetano Finocchiaro, Simona Frigerio
      An Optimized Method for Manufacturing a Clinical Scale Dendritic Cell-Based Vaccine for the Treatment of Glioblastoma
      PLOS ONE, December 2012, Volume 7, Issue 12, e52301.
      download pdf (120 KB)
  • Giangaspero F.
    Molecular stratification of high-grade gliomas in children.
    download pdf (82 KB)
    • Buttarelli FR, Massimino M, Antonelli M, Lauriola L, Nozza P, Donofrio V, Arcella A, Oliva MA, Di Rocco C, Giangaspero F.
      Evaluation status and prognostic significance of O6-methylguanine-DNA methyltransferase (MGMT) promoter methylation in pediatric high grade gliomas.
      Childs Nerv Syst. 2010 Aug;26(8):1051-6. Epub 2010 Jun 16.
    • Antonelli M, Buttarelli FR, Arcella A, Nobusawa S, Donofrio V, Oghaki H, Giangaspero F.
      Prognostic significance of histological grading, p53 status, YKL-40 expression, and IDH1 mutations in pediatric high-grade gliomas.
      J Neurooncol. 2010 Sep;99(2):209-15. Epub 2010 Feb 21.
    • Manila Antonelli, Maura Massimino, Isabella Morra, Maria Luisa Garrè, Marina Paola Gardiman, Francesca Romana Buttarelli, Antonietta Arcella, Felice Giangaspero
      Epression of pERK and pAKT in pediatric high grade astrocytomas: Correlation with YKL40 and prognostic significance.
      Neuropathology 2011 Aug doi:10.1111/j.1440-1789.2011.01252.x.
      download pdf (69 KB)
    • Manuela Badiali, Vincent Gleize, Sophie Paris, Loredana Moi, Selma Elhouadani, Antonietta Arcella, Roberta Morace, Manila Antonelli, Francesca Romana Buttarelli, Dominique Figarella- Branger, Young-Ho Kim, Hiroko Ohgaki, Karima Mokhtari, Marc Sanson, Felice Giangaspero
      KIAA1549-BRAF Fusions and IDH Mutations Can Coexist in Diffuse Gliomas of Adults.
      Brain Pathology (2012) ISSN 1015-6305.
      download pdf (72 KB)
    • Manila Antonelli, Manuela Badiali, Francesca Romana Buttarelli, Caterina Baldi, V. Gleize, S. Paris, Loredana Moi, Paolo Nozza, Antonietta Arcella, Maura Massimino, Marc Sanson, Felice Giangaspero.
      KIAA1549: BRAF fusion gene in pediatric brain tumors of different histogenesis.
      Submitted to Brain Pathology (2013).
      download pdf (in italian) (44 KB)
  • Salsano E.
    Generation of immortalized cell lines of human medulloblastoma through the expression of a dominant negative form of TP53 gene.
    introduction: download pdf (80 KB)
    results: download pdf (in Italian) (63 KB)
    • Ettore Salsano, Rosina Paterra, Miriam Figus, Francesca Menghi, Emanuela Maderna, Bianca Pollo, Carlo Lazzaro Solero, Luca Massimi, Gaetano Finocchiaro
      Expression Profile of frizzled receptors in human medulloblastomas
      J Neurooncol 2011 Aug DOI 10.1007/s11060-011-0682-6.
      download pdf (144 KB)
  • Sardi I., la Marca G., Giovannini M.G., Malvagia S., Guerrini R., Genitori L., Massimino M., Aricò M.
    Morphine treatment permits doxorubicin hydrochloride to cross blood brain barrier in rat model.
    download pdf (68 KB)
    • Research project on pediatric brain tumors:
      "Alteration of the blood-brain barrier (BBB) using drugs that interact with the P-glycoprotein.
      New perspectives for the treatment of "poor-responder" brain tumors of the pediatric age".
      Progress Report June 2011.
      download pdf (in italian) (112 KB)
    • Assessment of the cytotoxic effects of the chemotherapeutic drugs used in the treatment of high-risk brain tumors of the pediatric age.
      download pdf (in italian) (84 KB)
    • L'Ondasetron facilita il passaggio della doxorubicina attraverso la barriera ematoencefalica in modello murino.
      download pdf (in italian) (53 KB)
    • Alterazioni della barriera Emato-Encefalica mediante farmaci che interagiscono con la MDR. Nuove prospettive per la cura dei tumori intrinseci del tronco encefalico.
      Stato di avanzamento Novembre 2013.
      download pdf (in italian) (59 KB)

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